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How Tadalafil Works

Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.

While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.

If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.

As a PDE5 inhibitor, Tadalafil blocks the action of PDE5, which allows more blood to flow into the penis when you become sexually excited.

Although erections that last several hours are still ongoing, your body processes that same natural process and produces erections that are sufficient for sex.

Although these erections are not always successful, they often last and are even known as firm enough for sex.

If you think you’re having an ED medication-related medical condition, you can learn more about it in the.

What Is Tadalafil

Tadalafil is a proven and effective treatment for ED. It belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. These medications work by relaxing the blood vessels in the penis, allowing more blood to flow into it when you get sexually excited.

Taking Tadalafil for ED

If you’re considering taking Tadalafil for ED, having a check-up with your doctor is important. That’s especially important if you’re pregnant, if you’re trying to get pregnant, or if you're taking medications to treat blood pressure. If you have a medical condition that’s likely to affect you if you're taking Tadalafil, you can speak with our healthcare providers about it.

If you ever experience difficulties falling or staying asleep, it’s important to have an conversation with your healthcare provider. They can help you get an accurate diagnosis and suggest appropriate treatment if needed.

It’s also important to note that Tadalafil should not be taken by people who are allergic to it or take medications that could cause an allergic reaction. If you experience any side effects, discuss them with your healthcare provider.

If you miss a dose of Tadalafil, take it as soon as possible. If it’s almost time for your next dose, skip the missed dose. To ensure you receive the right dose of Tadalafil, take it as soon you remember it. Otherwise, you should expect it to be close to the time for your next dose.

Tadalafil Dosage

As you can see, there are different dosages of Tadalafil. And those are just the tip of the iceberg.

When taking Tadalafil, it’s very important to follow the recommended dosage instructions. The exact dosage can vary from person to person, but it typically ranges from 20 mg to 40 mg taken about once daily.

If you miss a dose, take it as soon as you can. However, if it is almost time for your next dose, skip the missed dose. Otherwise, take it as soon as possible. Do not take a double dose to make up for a missed one.

Tadalafil Side Effects

While Tadalafil is effective for treating ED, it can cause side effects in some people.

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How does Tadalafil save the day?

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What’s nextDoes Erectile Dysfunction stop a natural process?

The natural conclusion to this pattern is often not so clear. However, there are several possible explanations. One possibility is that underlying health conditions may prevent a medication from working effectively. However, there is also the risk of taking too much Tadalafil. In any case, there will be occasional incidents of dizziness or lightheadedness where the medication may not work as it should. For those who experience frequent side effects, these can be managed by taking extra care to adjust the treatment. Now, case in point, I am taking Tadalafil for chest pain as it provides effective and safe treatment.

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Product Description

TADALAFIL 100MG TABLETis a Tadalafil (Cialis) 20mg drug that is used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) in men. Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil works by increasing blood flow to the penis, helping men with ED to achieve and maintain an erection during sexual stimulation. It is available in two forms: a film-coated tablet and a gelatin capsule. The film-coated tablet is typically available in a blister pack of 60 tablets, with each pack containing 30 tablets. The gelatin capsule is usually taken 15 minutes before sexual activity and contains the same active ingredient as Tadalafil, but is less flexible than the Tadalafil tablet. Tadalafil is usually taken as a single dose or as a combination with another erectile dysfunction (ED) medication.

Key Features

  • Film-coated tablet
  • Gel-coated capsule
  • Inactive ingredients

What is Tadalafil (Cialis)?

Tadalafil is the active ingredient in a class of medications called PDE5 inhibitors. It works by relaxing the muscles in the blood vessels of the penis, allowing for increased blood flow during sexual stimulation. Tadalafil is available in 2 different forms, which are film-coated and gelatin capsule. The gelatin capsule is usually taken 15 minutes before sexual activity and contains the same active ingredient as Cialis.

Tadalafil (Cialis)

Tadalafil (Cialis) is an FDA-approved treatment for ED, with an FDA-approved indication for BPH. It works by increasing blood flow to the penis, helping men with ED to achieve and maintain an erection during sexual stimulation. Tadalafil is typically taken as a single dose or as a combination with another erectile dysfunction (ED) medication.

Tadalafil (Cialis) is the active ingredient in a class of medications called PDE5 inhibitors.

How to take Tadalafil (Cialis)?

Take Tadalafil (Cialis) by mouth as instructed by your doctor. Take Tadalafil (Cialis) approximately 30 minutes before sexual activity. Do not take Tadalafil (Cialis) more than once a day. If you experience side effects, such as headache, nausea, or dizziness, stop taking Tadalafil (Cialis) and seek emergency medical attention. If you are using any other medicines, stop taking Tadalafil (Cialis) and contact your doctor or pharmacist.

Do I need a prescription to take Tadalafil (Cialis)?

Tadalafil (Cialis) is available as a brand-name drug called Tadalafil. It is a prescription drug and should only be taken as prescribed by a doctor.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Karnit is a prescription medication used to manage cardiovascular conditions such as hypertension and some soft tissue injuries. It works by relaxing blood vessels, which helps improve blood flow and reduces blood pressure. Karnit is available in various doses, from 20mg to 400mg once daily. These doses are typically taken about 1 hour before anticipated sexual activity and once daily, to maintain stable blood pressure levels. Karnit is recommended during sexual activity and on an empty stomach.
  • Antacids: While taking antacids, Cialis can enhance the blood pressure-lowering effects of the medication, which include possible increased heart rate or dizziness. Avoid taking antacids in conjunction with Cialis.
  • Blood Pressure Medications: While Cialis is taken by mouth, certain blood pressure-lowering medications should be taken witholidonor (Norvasc, Amturnide, Diovan, Edendansil) or atazanavir (Serzone, Stenoplane), as they can increase side effects. Take it on an empty stomach or with a light meal about one hour before sexual activity and on an empty stomach or full stomach once daily.